| ORIGINAL ARTICLE |
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| Year : 2019 | Volume
: 10
| Issue : 4 | Page : 120-125 |
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Toxoplasmosis among blood donors: Unsafe blood transfusion in ibadan, southwest nigeria
Abimbola Amoo1, Kariuki Njaanake2, HO Dada-Adegbola3, Gloria Omosa-Manyonyi2
1 Department of Medical Microbiology and Parasitology, University of Ibadan, Ibadan, Nigeria; Department of Medical Microbiology, University of Nairobi, Nairobi, Kenya
2 Department of Medical Microbiology, University of Nairobi, Nairobi, Kenya
3 Department of Medical Microbiology and Parasitology, University of Ibadan, Ibadan, Nigeria
Correspondence Address:
Dr. Abimbola Amoo
Department of Medical Microbiology, University of Nairobi, Nairobi
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/joah.joah_31_19
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BACKGROUND: In Nigeria, there is paucity of data on transfusion-transmissible parasitic infections that can cause post-transfusion illness, especially in immunocompromised and transfusion-dependent patients. This study was designed to bridge the gap by screening for Toxoplasma gondii which can be transmitted by blood transfusion.
OBJECTIVES: The main objective of the study is to employ serology methods to screen blood donor's serum for T. gondii, in Blood Bank Transfusion Service Centre, Southwest Nigeria
MATERIALS AND METHODS: This is a cross-sectional study. Donor sera were tested for T. gondii infection using IgG and IgM enzyme-linked immunosorbent assay test kits.
RESULTS: A total of 248 donated blood sera were tested for T. gondii infection after storage. The seroprevalence of T.gondii IgG and IgM was 19.8% and 42.7%, respectively. There was a significant difference in anti-T. gondii IgM seroprevalence between vegetarian and generalists (3.2% vs. 40.8%; P < 0.002).
CONCLUSIONS: The anti-T. gondii IgM prevalence was relatively higher compared to anti-T. gondii IgG, implying the majority of seropositive donors had an acute or recent infection, might seroconvert to chronic infection. There was a lower seropositivity of T.gondii among vegetarian. |
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