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Year : 2013  |  Volume : 4  |  Issue : 2  |  Page : 84-86

Plasma cell myeloma with unusual presentations

Department of Pathology and Department of Medicine (MS Ramaiah medical college, India)

Correspondence Address:
Rashmi Krishnappa
No. 50/3 1st main, 1st cross, Nanjappa layout, Bangalore 560097

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Source of Support: None, Conflict of Interest: None

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In myeloma (Kahler's disease), most neoplastic plasma cells are easily recognizable and are thus diagnosed without difficulty. However, some of the cells may pose a considerable diagnostic problem, since they exhibit unusual cytological features that lead to erroneous diagnosis. Herein, we present 2 such cases. The first presented with cytomorphology similar to T-cell lymphoma/leukemia, due to the cerebriform nucleus. The second had an unusual clinical presentation of congestive heart failure with plasmablastic morphology leading to differential diagnosis of lymphoblastic lymphoma. Interestingly, both patients were negative for the Bence-Jones protein according to urinalysis, and the second case was negative for M (myeloma) band according to serum electrophoresis.

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