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  Indian J Med Microbiol
 

Figure 1: Madinah protocol for menstrual cycle control: (1) Hormonal therapy will continue on a daily basis. (2) At proposed time of menstruation (assigned by patient and physician), hormonal therapy will be stopped. (3) Antifibrinolytic drugs will be started. (4) With the first bleed, one dose recombinant activated factor VII will be given. (5) Keep monitoring bleeding, if a massive bleed occurs, recombinant activated factor VII will be initiated, and platelet transfusions will be avoided unless needed. (6) Hormonal therapy will restart between days 3 and 5. Antifibrinolytic drugs will continue until there are no more bleeds

Figure 1: Madinah protocol for menstrual cycle control: (1) Hormonal therapy will continue on a daily basis. (2) At proposed time of menstruation (assigned by patient and physician), hormonal therapy will be stopped. (3) Antifibrinolytic drugs will be started. (4) With the first bleed, one dose recombinant activated factor VII will be given. (5) Keep monitoring bleeding, if a massive bleed occurs, recombinant activated factor VII will be initiated, and platelet transfusions will be avoided unless needed. (6) Hormonal therapy will restart between days 3 and 5. Antifibrinolytic drugs will continue until there are no more bleeds