Year : 2019 | Volume
: 10 | Issue : 4 | Page : 120--125
Toxoplasmosis among blood donors: Unsafe blood transfusion in ibadan, southwest nigeria
Abimbola Amoo, Kariuki Njaanake, HO Dada-Adegbola, Gloria Omosa-Manyonyi
Department of Medical Microbiology and Parasitology, University of Ibadan, Ibadan, Nigeria; Department of Medical Microbiology, University of Nairobi, Nairobi, Kenya
BACKGROUND: In Nigeria, there is paucity of data on transfusion-transmissible parasitic infections that can cause post-transfusion illness, especially in immunocompromised and transfusion-dependent patients. This study was designed to bridge the gap by screening for Toxoplasma gondii which can be transmitted by blood transfusion.
OBJECTIVES: The main objective of the study is to employ serology methods to screen blood donor's serum for T. gondii, in Blood Bank Transfusion Service Centre, Southwest Nigeria
MATERIALS AND METHODS: This is a cross-sectional study. Donor sera were tested for T. gondii infection using IgG and IgM enzyme-linked immunosorbent assay test kits.
RESULTS: A total of 248 donated blood sera were tested for T. gondii infection after storage. The seroprevalence of T.gondii IgG and IgM was 19.8% and 42.7%, respectively. There was a significant difference in anti-T. gondii IgM seroprevalence between vegetarian and generalists (3.2% vs. 40.8%; P < 0.002).
CONCLUSIONS: The anti-T. gondii IgM prevalence was relatively higher compared to anti-T. gondii IgG, implying the majority of seropositive donors had an acute or recent infection, might seroconvert to chronic infection. There was a lower seropositivity of T.gondii among vegetarian.
Dr. Abimbola Amoo
Department of Medical Microbiology, University of Nairobi, Nairobi
|How to cite this article:|
Amoo A, Njaanake K, Dada-Adegbola H O, Omosa-Manyonyi G. Toxoplasmosis among blood donors: Unsafe blood transfusion in ibadan, southwest nigeria.J Appl Hematol 2019;10:120-125
|How to cite this URL:|
Amoo A, Njaanake K, Dada-Adegbola H O, Omosa-Manyonyi G. Toxoplasmosis among blood donors: Unsafe blood transfusion in ibadan, southwest nigeria. J Appl Hematol [serial online] 2019 [cited 2020 Apr 4 ];10:120-125
Available from: http://www.jahjournal.org/article.asp?issn=1658-5127;year=2019;volume=10;issue=4;spage=120;epage=125;aulast=Amoo;type=0