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CASE REPORT
Year : 2017  |  Volume : 8  |  Issue : 2  |  Page : 79-81

Acquired hemophilia A: A case report


1 Assistant Professor, Department of Pathology (Hematology Division), IMS & SUM Hospital, Bhubaneswar, Odisha, India
2 Assistant Professor, Department of Radiology, IMS & SUM Hospital, Bhubaneswar, Odisha, India

Correspondence Address:
Sarita Pradhan
Department of Pathology (Hematology Division), IMS & SUM Hospital, Bhubaneswar, 751003, Odisha
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/joah.joah_2_17

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Acquired hemophilia A is a rare autoimmune disorder where autoantibodies are produced against factor VIII. Its reported incidence is as low as 1.20 to 1.48 cases per million per years. However, this entity is underreported because diagnosis is often missed in routine practice as its symptoms differ from its congenital counterpart. We report a 25-year-old male who presented with proptosis of left eye and gastric outlet obstruction. Routine workup revealed isolated elevation of activated platelet thromboplastin time. The patient, however, did not have any history of bleeding episodes, and family history was also negative. Mixing studies and inhibitor screening revealed presence of inhibitors. High degree of clinical suspicion is required to correctly diagnose this rare entity presenting with variable bleeding manifestations.


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