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REVIEW ARTICLE
Year : 2013  |  Volume : 4  |  Issue : 4  |  Page : 125-130

Advances in pregnancy management in carriers of hemophilia


1 Departments of Obstetrics and Gynaecology; The Haemophilia Centre and Thrombosis Unit, Royal Free Hospital, Hampstead, London, UK
2 The Haemophilia Centre and Thrombosis Unit, Royal Free Hospital, Hampstead, London, UK
3 Medical Thrombosis and Haemophilia Treatment Centre, Duisburg, Germany

Correspondence Address:
Rezan Abdul-Kadir
The Haemophilia Centre and Thrombosis Unit, Royal Free Hospital, Pond Street, Hampstead, London, NW3 2QG, UK

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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1658-5127.127894

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Recent advances in prenatal diagnosis and multidisciplinary management has improved the reproductive outlook for carriers of hemophilia and their offspring. Pre-pregnancy planning allows the woman and her partner to explore reproductive options and prepares the family for the potential delivery of an affected male infant. Non-invasive methods of prenatal diagnosis are advancing, with the aim of providing a definitive test for hemophilia. Carriers of hemophilia have an increased risk of primary and secondary postpartum hemorrhage. The affected male offspring is potentially at risk of cranial bleeding during delivery. A multidisciplinary approach provides advanced planning for the optimum mode of delivery and provision of appropriate haemostatic cover to reduce the risk of bleeding complications. This review summarises current recommendations for pregnancy management in carriers of hemophilia, from the initial pre-pregnancy counseling through to delivery and care of the neonate.


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