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CASE REPORT
Year : 2013  |  Volume : 4  |  Issue : 1  |  Page : 39-41

A case of inferior vena cava filter thrombosis in a 37-year-old man with polycythemia vera and beta-thalassemia minor


1 Department of Medicine, Yale-New Haven Hospital
2 Sackler, School of Medicine
3 Department of Medicine, North Shore-LIJ Health System
4 Department of Medicine, Stony Brook University Medical Center

Date of Web Publication23-Jun-2014

Correspondence Address:
Michael Nanna
Yale-New Haven Hospital, Department of Internal Medicine, Traditional Residency Training Program, 20 York Street, New Haven, CT 06510

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Source of Support: None, Conflict of Interest: None


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  Abstract 

We report a case of a 37-year-old man presenting with painful bilateral lower extremity edema and scrotal swelling that had persisted for 1 month. The patient had a medical history of bilateral pulmonary emboli. He was treated with inferior vena cava (IVC) filter placement and warfarin, and his course was complicated by heparin-induced thrombocytopenia and subsequent pulmonary hypertension, which necessitated pulmonary endarterectomy. His medical history included beta-thalassemia minor, with concurrent Janus kinase 2-positive polycythemia rubra vera (PRV). At the time of his present admission, a computed tomography scan revealed that the patient had bilateral iliac vein thrombosis and IVC thrombosis, with bilateral varicoceles. After an unsuccessful trial treatment with warfarin, the patient was treated with fondaparinux, and his condition improved clinically before he was discharged on hospital day 8. This is the first reported case of concurrent beta-thalassemia minor and polycythemia rubra vera in a male patient; it highlights the possible thrombotic risk associated with PRV, even in patients with normal red blood cell mass.

Keywords: Thrombosis, Polycythemia rubra vera, beta-thalassemia


How to cite this article:
Nanna M, Nanna GJ, Chen R, Huang GJ. A case of inferior vena cava filter thrombosis in a 37-year-old man with polycythemia vera and beta-thalassemia minor. J Appl Hematol 2013;4:39-41

How to cite this URL:
Nanna M, Nanna GJ, Chen R, Huang GJ. A case of inferior vena cava filter thrombosis in a 37-year-old man with polycythemia vera and beta-thalassemia minor. J Appl Hematol [serial online] 2013 [cited 2020 Jan 23];4:39-41. Available from: http://www.jahjournal.org/text.asp?2013/4/1/39/135146

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