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 Table of Contents  
CASE REPORT
Year : 2012  |  Volume : 3  |  Issue : 2  |  Page : 86-88

Acquired Deficiency of Von Willebrand Factor- Cleaving Protease in an HIV-Infected Patient with Relapsing Thrombotic Thrombocytopenic Purpura


1 Department of Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
2 Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
3 Oncology Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia

Date of Web Publication26-Jun-2014

Correspondence Address:
Abdullah Alqaraawi
Resident, Department of Medicine, King Faisal Specialist Hospital and Research Center, Riyadh
Saudi Arabia
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Source of Support: None, Conflict of Interest: None


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  Abstract 

Thrombotic thrombocytopenic purpura (TTP) can result from a deficiency of von Willebrand factor-cleaving protease (vWF-cp) activity. Patients infected with human immunodeficiency virus (HIV) can present with acquired vWF-cp deficiency. We report a case of an HIV-infected woman who presented with relapsing thrombotic thrombocytopenic purpura (TTP) and was found to have an acquired ADAMTS 13 inhibitor. She was treated with plasma exchange and highly active antiretroviral therapy, which led to fewer clinical relapses.

Keywords: HIV, TTP, von Willebrand factor-cleaving protease


How to cite this article:
Alqaraawi A, Owaidah T, Alenzai A, Shad A, Almohareb F, Alhuraiji A, Alrajhi AA. Acquired Deficiency of Von Willebrand Factor- Cleaving Protease in an HIV-Infected Patient with Relapsing Thrombotic Thrombocytopenic Purpura. J Appl Hematol 2012;3:86-8

How to cite this URL:
Alqaraawi A, Owaidah T, Alenzai A, Shad A, Almohareb F, Alhuraiji A, Alrajhi AA. Acquired Deficiency of Von Willebrand Factor- Cleaving Protease in an HIV-Infected Patient with Relapsing Thrombotic Thrombocytopenic Purpura. J Appl Hematol [serial online] 2012 [cited 2020 Jun 2];3:86-8. Available from: http://www.jahjournal.org/text.asp?2012/3/2/86/135522

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