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Year : 2011  |  Volume : 2  |  Issue : 4  |  Page : 280-283

Improving the safety of plasma and its components for clinical transfusion

1 Shabrawishi Hospital Blood Transfusion Center

Correspondence Address:
MD Magdy El Ekiaby,
Shabrawishi Hospital Blood Transfusion Center

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Source of Support: None, Conflict of Interest: None

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Plasma and its components are prepared from whole blood or collected using apheresis. They represent important clinical transfusion products that contribute to the management of a variety of clinical cases. In addition, plasma is used by the fractionation industry to prepare many medicinal products. As with any medicinal product, safety, efficacy, and availability are essential elements that contribute to the support of patients who need plasma and its components. Good manufacturing practice is essential for the preparation of plasma and its components. To maximize benefits and reduce hazards, adherence to practice guidelines, which are developed from evidence-based medicine, is essential. Mini-pool solvent detergent pathogen inactivation with a single-use Conformité Européenne-marked medical device that can be used in local blood establishments and its validation are discussed in this review as new technology for making safe plasma and its products accessible to the developing as well as the developed world.

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